Why you only need 4 tablets misoprostol 24 hours after using Mifepristone

In 2006 when Women on Web started its online medical abortion service, medical abortion with 1 mifepristone and 4 misoprostol tablets was only registered till 7 weeks of pregnancy.

But since then a lot of scientific research has shown that an abortion with the pills 1 Mifepristone and 24 hours later 4 tablets of Misoprostol 200 microgram under the tongue is safe and effective for home use till 10 weeks without the need of repeated dosis of Misoprostol. Some studies even show that 2 tablets misoprostol is enough.

Women on Web follows the World Health Organisation guidelines. Most packages still contain 1 tablet of Mifepristone and up to 8 tablets of Misoprostol 200 mcg for women who are expected to be less than 10 weeks pregnant when they do the abortion with pills. This way more Misoprostol can be used whenever doubts rise if the procedure has started well. An extra dose of 2 Misoprostol 200 mcg can also be used for treatment of heavy bleeding or incomplete abortion.

Women who are longer than 10 weeks, will receive 1 tablet of Mifepristone and 12 tablets of Misoprostol 200mcg which should be used in repeated doses. In that case the woman will receive an email with the proper information how to use the extra tablets of misoprostol.

In some countries Misoprostol is available only in tablets of 400 mcg. When these pills are used for medical abortion, the number of Misoprostol tablets used should be halved.